Lifestyle: Weekend FT, Gel Botox coming soon

Weekend FT

July 19, 2008

By Julie Earle-Levine

Ever since the 1990s, the anti-wrinkle drug Botox has reigned supreme in the fight against unwanted lines. Many have deemed it and one of its competitors, Myobloc (another drug that uses botulinum toxin to block nerve impulses and "freeze" lines), heaven-sent.

But now the US Food and Drug Administration (FDA) is investigating the product and has warned of possible side effects and even deaths related to Botox use.

According to the consumer advocacy group Public Citizen, there have been at least 16 deaths among 658 reported cases of people in the US "suffering adverse affects from Botox" between November 1997 and December 2006. The FDA is currently reviewing data from clinical studies by the drugs' manufacturers and expects to issue a report in several months.

Public Citizen's initial findings suggest that the use of Botox for cosmetic purposes does not lead to as great a risk of adverse effects as for other "off-label" uses, which would include using treating limb spasticity in a child with cerebral palsy. But the FDA has warned that people using Botox cosmetically should be aware of potential adverse effects, which include breathing problems.

The issue is enough to make consumer groups such as Public Citizen ask that doctors be required to give patients a written warning each time they receive a Botox injection. Last year, drug regulators in the UK and Germany required sterner warnings to be sent to doctors in those countries regarding its use. In France, the government requires doctors to have surgical qualifications to use Botox. Amidst all this, Allergan, the maker of Botox, has said that adverse reactions are rare. "In its entire history, there has never been a single reported death where a causal link to cosmetic Botox was established," said Dr Sef Kurstjens, Allergan's chief medical officer.

Talk of side effects does not appear to be deterring current clients, at least according to Dr David Goldberg, a Manhattan dermatologist and director of the Skin Laser clinic in New York. Goldberg has been offering Botox for more than 10 years and estimates that it makes up 20 per cent of his business. "About 75 per cent of people keep having Botox once they have tried it," says Goldberg of his mainly female client base.

But for those fighting shy of the needle or who would prefer to wait for the results of the FDA investigation, there are plenty of Botox-inspired products on the market - even if the results are not as long-lasting.

For instance, "Glamotox", which contains hyaluronic acid, promises to plump up the skin while you sleep. One recent convert already swears by it. "I'm addicted. It makes me look younger, without having to get Botox or laser," she enthuses.

"Freeze 24/7" is another highly popular moisturiser that professes to freeze wrinkles for up to eight hours, giving the effect of an eye lift - albeit briefly.

Meanwhile, the sale of topical Botox in a gel form - which can be applied to the skin rather than injected - is also a looming reality.

"The intention is to get rid of wrinkles but to preserve facial expression," says Dan Browne, chief executive of Revance, the US-based biopharmaceutical company behind the development. It is currently conducting clinical trials to see whether the gel will have fewer possible side effects than injected Botox.

According to Browne, Botox gel could become a huge chunk of the rapidly growing $14bn facial aesthetic markets. The cool gel will warm up on the skin and, as with Botox, result in visible changes after 24 to 72 hours, with "peak activity" after one week. But the gel would be prescribed and applied by a doctor, meaning you could not just apply it casually at home.

ends

Lifestyle: New York magazine - Polo's Nacho Figueras

Nacho Figueras Explains Polo to Us

Photo: Getty Images

July14, 2008

The Hamptons polo season starts this Saturday, and one of the world’s most famous players, occasional Ralph Lauren model Nacho Figueras, moves into his Sag Harbor summer rental to prepare. (Okay, let's face it, he's the only famous polo player. Why is he the only one anyone ever talks about? Because he's hot? Okay, that's fair.) He’ll be playing in Bridgehampton each Saturday through mid-August. The eternally adorable Argentine explained the appeal of the game to Julie Earle-Levine and answered our ultimate burning questions about polo: Isn't it really just about wearing pastel and drinking Champagne? (Answer: apparently not.)

Does anyone in the U.S. actually follow polo?
New Yorkers are obviously very into baseball and football, but I think that New Yorkers are very open-minded, so they are really into any sports.

But isn’t the polo thing really just about the Hamptons social scene?
No! Polo is a sport that is very underrated and has a lot more to offer. It is a great thing to do with family. I play polo with my son, who is 8 years old. He is learning the sport. It is a very special thing. The bond you have with horses is very, very special. They are wonderful creatures. You cannot be a polo player unless you have special relationship with horses.

And you think the Bridgehampton crowd appreciates that bond?
Of course some people are there to socialize. But after the matches, many people come up and tell me about the game, and I realize they have been following it. When I first got to America, in 1999, I couldn’t understand baseball. It is the same with polo. You need to learn the game and watch it. Then you can appreciate it.

Is it played in places more accessible to normal people than the Hamptons and Greenwich?
You need room, like fourteen acres. There is a polo club in Meadow Brook, Long Island, a club in Greenwich, and a club in Millbrook, upstate New York.

And the crowd seems to be all models, media barons, and hedge-fund guys.
I think polo is for everyone. Polo is for kids, family, and everyone. Polo is a sport that brings together people from all over the world. I mean, a guy like me, from middle-class family in Argentina, I met the Queen and played polo there, and then I spend a lot of time with the grooms in the barns.

ends

Travel: Departures - Explorers Issue

Departures, July/August 2008

By Julie Earle-Levine

Southern Ocean Lodge, Kangaroo Island – ‘Way Down Under’

SOUTH Australia’s Kangaroo Island – home to some of the continent’s most intriguing wildlife – has long been popular with the day-tripping and camping crowd. It never had any luxury accommodation until this spring, however, when James and Hayley Baillie, owners of the chic Capella Lodge on Oz’s Lord Howe Island, opened their new property, Southern Ocean Lodge.

Set between two national parks on the island’s isolated southwest coast and just a 25 minute flight from Adelaide, the property is nestled in the bush and has expansive views of the turquoise blue sea below. Of the lodge’s 25 minimalist rooms, the best is the Osprey Pavilion, with its hand-sculpted, egg-shaped Japanese bathtub and private terrace. From its alfresco daybeds and plunge spa, guests have a prime view of passing kangaroos and whales out at sea.

But those who come to K.I. almost always want to get closer to the wildlife. And so the Baillies partnered with local outfitter Exceptional Kangaroo Island to take visitors to the area’s singular landscape (the animal-spotting is so good here and so easy here that it’s really a shame the lodge doesn’t allow children younger than six). Our stellar and slightly wacky guide, Anthony, aka Ants, who has lived on the island for 18 years, led our small group on a half-day journey, pointing out plump koalas perched on impossibly thin branches, kangaroo mothers hopping about with their in-pouch babes, and even the elusive glossy black cockatoo – or at least evidence thereof, in the form of some nibbled seeds.

On a separate hike, a trip to see Australian fur seals preceded a light lunch served rather glamorously under a white shade tent and accompanied by a local Chardonnay.

Later, a stylish New Yorker who had just arrived at the lodge from Sydney was wondering aloud when she might see a kangaroo. She didn’t have to wait long though. During a twilight tour with lodge staff, glass of champagne in hand, she was suddenly surrounded by dozens of curious ‘rooms and wallabies. “I didn’t really expect to see wildlife like this,’ she said, laughing. But at Southern Ocean Lodge that’s just the kind of champagne wishes and kangaroo dreams experience that guests are in for.

Rates begin at A$900 per night (two night minimum) and include meals. Southernoceanlodge.com.au